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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D23
All Species:
15.45
Human Site:
S459
Identified Species:
30.91
UniProt:
Q9NUY8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUY8
NP_060779.2
699
78322
S459
G
Y
G
H
W
I
A
S
T
S
G
S
R
S
S
Chimpanzee
Pan troglodytes
XP_001142898
699
78360
S459
G
Y
G
H
W
I
A
S
T
S
G
S
R
S
S
Rhesus Macaque
Macaca mulatta
XP_001089575
699
78401
S459
G
Y
G
H
W
I
A
S
T
S
G
S
R
S
S
Dog
Lupus familis
XP_535717
699
78459
S459
G
Y
G
H
W
I
A
S
T
S
G
S
R
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0F1
684
76407
I444
L
Q
Q
H
L
A
D
I
N
V
E
G
P
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518998
1159
128900
V919
Q
H
L
A
D
I
N
V
D
G
P
E
N
G
Y
Chicken
Gallus gallus
Q5F415
679
75993
V439
Q
H
L
A
D
I
N
V
E
G
P
E
N
G
Y
Frog
Xenopus laevis
Q6NRC7
682
76832
S442
G
H
W
I
V
S
T
S
G
S
H
S
S
I
S
Zebra Danio
Brachydanio rerio
Q7SXV1
680
76081
D439
A
L
Q
Q
H
L
A
D
I
N
V
E
G
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608569
689
77454
C450
E
D
H
N
A
R
K
C
L
V
C
Q
Q
H
N
Honey Bee
Apis mellifera
XP_624741
648
73025
Q413
M
V
V
A
S
F
L
Q
K
H
T
Q
Y
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788039
808
91017
L485
G
M
I
D
P
A
I
L
K
S
V
I
I
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.1
96.4
N.A.
92.1
N.A.
N.A.
54.6
87.1
80.2
75.2
N.A.
44.9
41.3
N.A.
38.3
Protein Similarity:
100
99.4
99.1
98
N.A.
95.8
N.A.
N.A.
56.9
92.5
88.2
84.8
N.A.
61.7
59.7
N.A.
55
P-Site Identity:
100
100
100
100
N.A.
13.3
N.A.
N.A.
6.6
6.6
33.3
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
N.A.
N.A.
13.3
13.3
40
20
N.A.
20
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
25
9
17
42
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
9
17
0
9
9
9
0
0
0
0
0
9
% D
% Glu:
9
0
0
0
0
0
0
0
9
0
9
25
0
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
34
0
0
0
0
0
9
17
34
9
9
17
0
% G
% His:
0
25
9
42
9
0
0
0
0
9
9
0
0
9
0
% H
% Ile:
0
0
9
9
0
50
9
9
9
0
0
9
9
9
0
% I
% Lys:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% K
% Leu:
9
9
17
0
9
9
9
9
9
0
0
0
0
0
0
% L
% Met:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
17
0
9
9
0
0
17
0
9
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
17
0
9
9
0
% P
% Gln:
17
9
17
9
0
0
0
9
0
0
0
17
9
0
9
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
34
0
0
% R
% Ser:
0
0
0
0
9
9
0
42
0
50
0
42
9
34
59
% S
% Thr:
0
0
0
0
0
0
9
0
34
0
9
0
0
9
0
% T
% Val:
0
9
9
0
9
0
0
17
0
17
17
0
0
9
0
% V
% Trp:
0
0
9
0
34
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
0
0
0
0
0
0
0
0
0
0
9
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _